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Both the SH2 and SH3 domains of human CRK protein are required for neuronal differentiation of PC12 cells.

Human CRK protein is a homolog of the chicken v-crk oncogene product and consists mostly of src homology region 2 (SH2) and SH3, which are shared by many proteins, in particular those involved in signal transduction. SH2 has been shown to bind specifically to phosphotyrosine-containing peptides. We...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Tanaka, S, Hattori, S, Kurata, T, Nagashima, K, Fukui, Y, Nakamura, S, Matsuda, M
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1993
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Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360008/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8321240/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.7.4409-4415.1993
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