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Nuclear Accumulation of p21(Cip1) at the Onset of Mitosis: a Role at the G(2)/M-Phase Transition

Cell cycle arrest in G(1) in response to ionizing radiation or senescence is believed to be provoked by inactivation of G(1) cyclin-cyclin-dependent kinases (Cdks) by the Cdk inhibitor p21(Cip1/Waf1/Sdi1). We provide evidence that in addition to exerting negative control of the G(1)/S phase transiti...

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Detalhes bibliográficos
Main Authors: Dulić, Vjekoslav, Stein, Gretchen H., Far, Dariush Farahi, Reed, Steven I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC121522/
https://ncbi.nlm.nih.gov/pubmed/9418901
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