Isolation and Characterization of New Alleles of the Cyclin-Dependent Kinase Gene CDC28 with Cyclin-Specific Functional and Biochemical Defects

The G(1) cyclin Cln2 negatively regulates the mating-factor pathway. In a genetic screen to identify factors required for this regulation, we identified an allele of CDC28 (cdc28-csr1) that blocked this function of Cln2. Cln2 immunoprecipitated from cdc28-csr1 cells was completely defective in histo...

Full description

Bibliographic Details

Published in:	Mol Cell Biol
Main Authors:	Levine, Kristi, Oehlen, L. J. W. M., Cross, Frederick R.
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 1998
Subjects:	Cell Growth and Development
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121493/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9418876/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.1.290
Tags:	Add Tag No Tags, Be the first to tag this record!