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Isolation and Characterization of New Alleles of the Cyclin-Dependent Kinase Gene CDC28 with Cyclin-Specific Functional and Biochemical Defects

The G(1) cyclin Cln2 negatively regulates the mating-factor pathway. In a genetic screen to identify factors required for this regulation, we identified an allele of CDC28 (cdc28-csr1) that blocked this function of Cln2. Cln2 immunoprecipitated from cdc28-csr1 cells was completely defective in histo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Levine, Kristi, Oehlen, L. J. W. M., Cross, Frederick R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 1998
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC121493/
https://ncbi.nlm.nih.gov/pubmed/9418876
Tagiau: Ychwanegu Tag
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