Isolation and Characterization of New Alleles of the Cyclin-Dependent Kinase Gene CDC28 with Cyclin-Specific Functional and Biochemical Defects

The G(1) cyclin Cln2 negatively regulates the mating-factor pathway. In a genetic screen to identify factors required for this regulation, we identified an allele of CDC28 (cdc28-csr1) that blocked this function of Cln2. Cln2 immunoprecipitated from cdc28-csr1 cells was completely defective in histo...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Levine, Kristi, Oehlen, L. J. W. M., Cross, Frederick R.
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1998
Sujets:	Cell Growth and Development
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121493/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9418876/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.1.290
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