Isolation and Characterization of New Alleles of the Cyclin-Dependent Kinase Gene CDC28 with Cyclin-Specific Functional and Biochemical Defects

The G(1) cyclin Cln2 negatively regulates the mating-factor pathway. In a genetic screen to identify factors required for this regulation, we identified an allele of CDC28 (cdc28-csr1) that blocked this function of Cln2. Cln2 immunoprecipitated from cdc28-csr1 cells was completely defective in histo...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Levine, Kristi, Oehlen, L. J. W. M., Cross, Frederick R.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1998
Soggetti:	Cell Growth and Development
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121493/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9418876/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.1.290
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