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Expression of activation-induced cytidine deaminase is regulated by cell division, providing a mechanistic basis for division-linked class switch recombination

Class switch recombination (CSR) is the process by which B cells alter the effector function properties of their Ig molecules. The decision to switch to a particular Ig isotype is determined primarily by the mode of B cell activation and cytokine exposure. More recent work indicates that the likelih...

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Bibliografiska uppgifter
Huvudupphovsmän: Rush, James S., Liu, Man, Odegard, Valerie H., Unniraman, Shyam, Schatz, David G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2005
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201576/
https://ncbi.nlm.nih.gov/pubmed/16141332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502779102
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