Sortilin Controls Intracellular Sorting of Brain-Derived Neurotrophic Factor to the Regulated Secretory Pathway

Brain-derived neurotrophic factor (BDNF), after activity-dependent secretion from neurons, modulates critical nervous system functions. Recently, a variant in the human bdnf gene, resulting in a valine to methionine substitution in the prodomain, has been shown to lead to defective regulated secreti...

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Hlavní autoři: Chen, Zhe-Yu, Ieraci, Alessandro, Teng, Henry, Dall, Henning, Meng, Chui-Xiang, Herrera, Daniel G., Nykjaer, Anders, Hempstead, Barbara L., Lee, Francis S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2005
Témata:
Cellular/Molecular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201519/
https://ncbi.nlm.nih.gov/pubmed/15987945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1017-05.2005
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