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Virulence of the Fungal Pathogen Candida albicans Requires the Five Isoforms of Protein Mannosyltransferases

The PMT gene family in Candida albicans encodes five isoforms of protein mannosyltransferases (Pmt proteins Pmt1p, Pmt2p, Pmt4p, Pmt5p, and Pmt6p) that initiate O mannosylation of secretory proteins. We compared virulence characteristics of pmt mutants in two complex, three-dimensional models of loc...

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Bibliografske podrobnosti
Main Authors: Rouabhia, Mahmoud, Schaller, Martin, Corbucci, Cristina, Vecchiarelli, Anna, Prill, Stephan K.-H., Giasson, Luc, Ernst, Joachim F.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201229/
https://ncbi.nlm.nih.gov/pubmed/16040968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.8.4571-4580.2005
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