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Sch9 Kinase Integrates Hypoxia and CO(2) Sensing To Suppress Hyphal Morphogenesis in Candida albicans
The yeast-hypha transition is an important virulence trait of Candida albicans. We report that the AGC kinase Sch9 prevents hypha formation specifically under hypoxia at high CO(2) levels. sch9 mutants showed no major defects in growth and stress resistance but a striking hyperfilamentous phenotype...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3127645/ https://ncbi.nlm.nih.gov/pubmed/21335533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00289-10 |
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