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Sch9 Kinase Integrates Hypoxia and CO(2) Sensing To Suppress Hyphal Morphogenesis in Candida albicans

The yeast-hypha transition is an important virulence trait of Candida albicans. We report that the AGC kinase Sch9 prevents hypha formation specifically under hypoxia at high CO(2) levels. sch9 mutants showed no major defects in growth and stress resistance but a striking hyperfilamentous phenotype...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Stichternoth, Catrin, Fraund, Alida, Setiadi, Eleonora, Giasson, Luc, Vecchiarelli, Anna, Ernst, Joachim F.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127645/
https://ncbi.nlm.nih.gov/pubmed/21335533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00289-10
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