Protein O-Mannosyltransferase Isoforms Regulate Biofilm Formation in Candida albicans

Five isoforms of protein mannosyltransferase (Pmt) O-mannosylate secretory proteins in Candida albicans. pmt mutants were differentially defective for biofilm formation on plastic in static and flow-through systems, and a Pmt inhibitor blocked early stages of biofilm formation. Conceptually, Pmt inh...

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Detalhes bibliográficos
Main Authors: Peltroche-Llacsahuanga, Heidrun, Goyard, Sophie, d′Enfert, Christophe, Prill, Stephan K.-H., Ernst, Joachim F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1610076/
https://ncbi.nlm.nih.gov/pubmed/17005840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00606-06
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