Virulence of the Fungal Pathogen Candida albicans Requires the Five Isoforms of Protein Mannosyltransferases

The PMT gene family in Candida albicans encodes five isoforms of protein mannosyltransferases (Pmt proteins Pmt1p, Pmt2p, Pmt4p, Pmt5p, and Pmt6p) that initiate O mannosylation of secretory proteins. We compared virulence characteristics of pmt mutants in two complex, three-dimensional models of loc...

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Autori principali: Rouabhia, Mahmoud, Schaller, Martin, Corbucci, Cristina, Vecchiarelli, Anna, Prill, Stephan K.-H., Giasson, Luc, Ernst, Joachim F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
Soggetti:
Fungal and Parasitic Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201229/
https://ncbi.nlm.nih.gov/pubmed/16040968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.8.4571-4580.2005
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