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Mathematical Assumptions versus Biological Reality: Myths in Affected Sib Pair Linkage Analysis
Affected sib pair (ASP) analysis has become common ever since it was shown that, under very specific assumptions, ASPs afford a powerful design for linkage analysis. In 2003, Vieland and Huang, on the basis of a “fundamental heterogeneity equation,” proved that heterogeneity and epistasis are confou...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The American Society of Human Genetics
2005
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1196418/ https://ncbi.nlm.nih.gov/pubmed/15540158 |
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