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Asymptotic properties of affected-sib-pair linkage analysis.
The likelihood-ratio method for affected-sib-pair analysis, introduced by Risch, is a powerful method for detecting linkage when the marker is not perfectly polymorphic, as is often the case. The power of this method can be improved by restricting maximization to the set of possible haplotype-sharin...
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1993
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1682211/ https://ncbi.nlm.nih.gov/pubmed/8430697 |
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