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Linkage analysis of alcohol dependence using both affected and discordant sib pairs
The basic idea of affected-sib-pair (ASP) linkage analysis is to test whether the inheritance pattern of a marker deviates from Mendelian expectation in a sample of ASPs. The test depends on an assumed Mendelian control distribution of the number of marker alleles shared identical by descent (IBD),...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2005
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1866749/ https://ncbi.nlm.nih.gov/pubmed/16451646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-S1-S36 |
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