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Nonpaternity in Linkage Studies of Extremely Discordant Sib Pairs

An approach commonly used to increase statistical power in linkage studies is the study of extremely discordant sibling pairs. This design is powerful under both additive and dominant-gene models and across a wide range of allele frequencies. A practical problem with the design is that extremely dis...

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Detalhes bibliográficos
Main Authors: Neale, Michael C., Neale, Benjamin M., Sullivan, Patrick F.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics. 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC384925/
https://ncbi.nlm.nih.gov/pubmed/11745068
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