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Coordinated Replication and Sequestration of oriC and dnaA Are Required for Maintaining Controlled Once-per-Cell-Cycle Initiation in Escherichia coli

Escherichia coli cells were constructed in which the dnaA gene was moved to a location opposite oriC on the circular chromosome. In these cells the dnaA gene was replicated with significant delay relative to the origin. Consequently, the period where the newly replicated and hemimethylated oriC was...

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Bibliografiske detaljer
Main Authors: Riber, Leise, Løbner-Olesen, Anders
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196069/
https://ncbi.nlm.nih.gov/pubmed/16077105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.16.5605-5613.2005
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