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Coordinated Replication and Sequestration of oriC and dnaA Are Required for Maintaining Controlled Once-per-Cell-Cycle Initiation in Escherichia coli

Escherichia coli cells were constructed in which the dnaA gene was moved to a location opposite oriC on the circular chromosome. In these cells the dnaA gene was replicated with significant delay relative to the origin. Consequently, the period where the newly replicated and hemimethylated oriC was...

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Detalhes bibliográficos
Main Authors: Riber, Leise, Løbner-Olesen, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196069/
https://ncbi.nlm.nih.gov/pubmed/16077105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.16.5605-5613.2005
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