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Coordinated Replication and Sequestration of oriC and dnaA Are Required for Maintaining Controlled Once-per-Cell-Cycle Initiation in Escherichia coli

Escherichia coli cells were constructed in which the dnaA gene was moved to a location opposite oriC on the circular chromosome. In these cells the dnaA gene was replicated with significant delay relative to the origin. Consequently, the period where the newly replicated and hemimethylated oriC was...

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Bibliographic Details
Main Authors: Riber, Leise, Løbner-Olesen, Anders
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196069/
https://ncbi.nlm.nih.gov/pubmed/16077105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.16.5605-5613.2005
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