Induction of the MexXY Efflux Pump in Pseudomonas aeruginosa Is Dependent on Drug-Ribosome Interaction

MexXY is an inducible efflux system that contributes to the natural resistance of Pseudomonas aeruginosa to antibiotics. Experiments involving real-time PCR after reverse transcription in reference strain PAO1 showed concentration-dependent induction of gene mexY by various ribosome inhibitors (e.g....

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Bibliographic Details
Main Authors: Jeannot, Katy, Sobel, Mara L., El Garch, Farid, Poole, Keith, Plésiat, Patrick
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Microbial Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196038/
https://ncbi.nlm.nih.gov/pubmed/16030228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.15.5341-5346.2005
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