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The Efflux Pump MexXY/OprM Contributes to the Tolerance and Acquired Resistance of Pseudomonas aeruginosa to Colistin

The intrinsic resistance of Pseudomonas aeruginosa to polymyxins in part relies on the addition of 4-amino-4-deoxy-l-arabinose (Ara4N) molecules to the lipid A of lipopolysaccharide (LPS), through induction of operon arnBCADTEF-ugd (arn) expression. As demonstrated previously, at least three two-com...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Puja, Hélène, Bolard, Arnaud, Noguès, Aurélie, Plésiat, Patrick, Jeannot, Katy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179290/
https://ncbi.nlm.nih.gov/pubmed/31964794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02033-19
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