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Enhanced NF-κB activation and cellular function in macrophages lacking IκB kinase 1 (IKK1)
IκB kinase (IKK) complex plays a key regulatory role in macrophages for NF-κB activation during both innate and adaptive immune responses. Because IKK1(–/–) mice died at birth, we differentiated functional macrophages from embryonic day 15.5 IKK1 mutant embryonic liver. The embryonic liver-derived m...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1194954/ https://ncbi.nlm.nih.gov/pubmed/16116086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505997102 |
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