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Impaired Development of CD4(+) CD25(+) Regulatory T Cells in the Absence of STAT1: Increased Susceptibility to Autoimmune Disease
Type I and II interferons (IFNs) exert opposing effects on the progression of multiple sclerosis, even though both IFNs use the signal transducer and activator of transcription 1 (STAT1) as a signaling mediator. Here we report that STAT1-deficient mice expressing a transgenic T cell receptor against...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1193645/ https://ncbi.nlm.nih.gov/pubmed/14699080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020509 |
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