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Absence of β2 Integrins Impairs Regulatory T Cells and Exacerbates CD4(+) T cell-Dependent Autoimmune Carditis
The immunopathogenic mechanisms mediating inflammation in multi-organ autoimmune diseases may vary between the different target tissues. We utilized the K/BxN TCR transgenic mouse model to investigate the contribution of CD4(+) T cells and β2 integrins in the pathogenesis of autoimmune arthritis and...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3159859/ https://ncbi.nlm.nih.gov/pubmed/21795599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000967 |
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