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Mechanisms of impaired regulation by CD4(+)CD25(+)FOXP3(+) regulatory T cells in human autoimmune diseases

A lack of regulatory T (T(Reg)) cells that express CD4, CD25 and forkhead box P3 (FOXP3) results in severe autoimmunity in both mice and humans. Since the discovery of T(Reg) cells, there has been intense investigation aimed at determining how they protect an organism from autoimmunity and whether d...

詳細記述

保存先:
書誌詳細
第一著者: Buckner, Jane Hoyt
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046807/
https://ncbi.nlm.nih.gov/pubmed/21107346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri2889
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