Essential Role of STAT1 in Caspase-Independent Cell Death of Activated Macrophages through the p38 Mitogen-Activated Protein Kinase/STAT1/Reactive Oxygen Species Pathway

Unlike other immune cells, activation of macrophages by stimulating agents, such as lipopolysaccharide (LPS), confers significant resistance to many apoptotic stimuli, but the underlying mechanism of this phenomenon remains largely unknown. Here, we demonstrate that LPS-induced early caspase activat...

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Detalhes bibliográficos
Main Authors: Kim, Hun Sik, Lee, Myung-Shik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190352/
https://ncbi.nlm.nih.gov/pubmed/16024814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.15.6821-6833.2005
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