Preventing local regeneration of glucocorticoids by 11β-hydroxysteroid dehydrogenase type 1 enhances angiogenesis

Angiogenesis restores blood flow to healing tissues, a process that is inhibited by high doses of glucocorticoids. However, the role of endogenous glucocorticoids and the potential for antiglucocorticoid therapy to enhance angiogenesis is unknown. Using in vitro and in vivo models of angiogenesis in...

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Autors principals: Small, Gary R., Hadoke, Patrick W. F., Sharif, Isam, Dover, Anna R., Armour, Danielle, Kenyon, Christopher J., Gray, Gillian A., Walker, Brian R.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1189304/
https://ncbi.nlm.nih.gov/pubmed/16093320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500641102
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