Preventing local regeneration of glucocorticoids by 11β-hydroxysteroid dehydrogenase type 1 enhances angiogenesis

Angiogenesis restores blood flow to healing tissues, a process that is inhibited by high doses of glucocorticoids. However, the role of endogenous glucocorticoids and the potential for antiglucocorticoid therapy to enhance angiogenesis is unknown. Using in vitro and in vivo models of angiogenesis in...

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Bibliografiske detaljer
Main Authors: Small, Gary R., Hadoke, Patrick W. F., Sharif, Isam, Dover, Anna R., Armour, Danielle, Kenyon, Christopher J., Gray, Gillian A., Walker, Brian R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1189304/
https://ncbi.nlm.nih.gov/pubmed/16093320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500641102
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