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Not so crystal clear: the structure of the human telomere G-quadruplex in solution differs from that present in a crystal

The structure of human telomere DNA is of intense interest because of its role in the biology of both cancer and aging. The sequence [5′-AGGG(TTAGGG)(3)] has been used as a model for telomere DNA in both NMR and X-ray crystallographic studies, the results of which show dramatically different structu...

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Detalhes bibliográficos
Main Authors: Li, Jing, Correia, John J., Wang, Lei, Trent, John O., Chaires, Jonathan B.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187823/
https://ncbi.nlm.nih.gov/pubmed/16106044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki782
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