An S101P Substitution in the Putative Cleavage Motif of the Human Metapneumovirus Fusion Protein Is a Major Determinant for Trypsin-Independent Growth in Vero Cells and Does Not Alter Tissue Tropism in Hamsters

Lignende værker

• Deletion of human metapneumovirus M2-2 increases mutation frequency and attenuates growth in hamsters
  af: Schickli, Jeanne H, et al.
  Udgivet: (2008)
• Recovery of Human Metapneumovirus Genetic Lineages A and B from Cloned cDNA
  af: Herfst, Sander, et al.
  Udgivet: (2004)
• Modification of the Trypsin-Dependent Cleavage Activation Site of the Human Metapneumovirus Fusion Protein To Be Trypsin Independent Does Not Increase Replication or Spread in Rodents or Nonhuman Primates
  af: Biacchesi, Stéphane, et al.
  Udgivet: (2006)
• A host-range restricted parainfluenza virus type 3 (PIV3) expressing the human metapneumovirus (hMPV) fusion protein elicits protective immunity in African green monkeys
  af: Tang, Roderick S., et al.
  Udgivet: (2005)
• Trypsin- and low pH-mediated fusogenicity of avian metapneumovirus fusion proteins is determined by residues at positions 100, 101 and 294
  af: Yun, Bingling, et al.
  Udgivet: (2015)