Deletion of human metapneumovirus M2-2 increases mutation frequency and attenuates growth in hamsters

BACKGROUND: Human metapneumovirus (hMPV) infection can cause acute lower respiratory tract illness in infants, the immunocompromised, and the elderly. Currently there are no licensed preventative measures for hMPV infections. Using a variant of hMPV/NL/1/00 that does not require trypsin supplementat...

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Библиографические подробности
Главные авторы: Schickli, Jeanne H, Kaur, Jasmine, MacPhail, Mia, Guzzetta, Jeanne M, Spaete, Richard R, Tang, Roderick S
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2008
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2426676/
https://ncbi.nlm.nih.gov/pubmed/18519001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-5-69
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