Effects of Human Metapneumovirus and Respiratory Syncytial Virus Antigen Insertion in Two 3′ Proximal Genome Positions of Bovine/Human Parainfluenza Virus Type 3 on Virus Replication and Immunogenicity

A live attenuated bovine parainfluenza virus type 3 (PIV3), harboring the fusion (F) and hemagglutinin-neuraminidase (HN) genes of human PIV3, was used as a virus vector to express surface glycoproteins derived from two human pathogens, human metapneumovirus (hMPV) and respiratory syncytial virus (R...

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Detalhes bibliográficos
Main Authors: Tang, Roderick S., Schickli, Jeanne H., MacPhail, Mia, Fernandes, Fiona, Bicha, Leenas, Spaete, Joshua, Fouchier, Ron A. M., Osterhaus, Albert D. M. E., Spaete, Richard, Haller, Aurelia A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC224993/
https://ncbi.nlm.nih.gov/pubmed/14512532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.20.10819-10828.2003
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