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Knockout mice reveal a tumor suppressor function for Testin

The Testin (TES) gene was previously identified as a putative human tumor suppressor gene at 7q31.2, a region that is frequently deleted in hematopoietic malignancies, as well as in epithelial tumors. To determine whether TES acts as a tumor suppressor in vivo, we generated a Tes knockout mouse and...

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Autors principals: Drusco, Alessandra, Zanesi, Nicola, Roldo, Claudia, Trapasso, Francesco, Farber, John L., Fong, Louise Y., Croce, Carlo M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182460/
https://ncbi.nlm.nih.gov/pubmed/16033868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504934102
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