Transgenic and Knockout Mice Models to Reveal the Functions of Tumor Suppressor Genes

Cancer is caused by multiple genetic alterations leading to uncontrolled cell proliferation through multiple pathways. Malignant cells arise from a variety of genetic factors, such as mutations in tumor suppressor genes (TSGs) that are involved in regulating the cell cycle, apoptosis, or cell differ...

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Autori principali: Taneja, Pankaj, Zhu, Sinan, Maglic, Dejan, Fry, Elizabeth A., Kendig, Robert D., Inoue, Kazushi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Libertas Academica 2011
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153120/
https://ncbi.nlm.nih.gov/pubmed/21836819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CMO.S7516
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