Transgenic and Knockout Mice Models to Reveal the Functions of Tumor Suppressor Genes

Cancer is caused by multiple genetic alterations leading to uncontrolled cell proliferation through multiple pathways. Malignant cells arise from a variety of genetic factors, such as mutations in tumor suppressor genes (TSGs) that are involved in regulating the cell cycle, apoptosis, or cell differ...

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Autors principals: Taneja, Pankaj, Zhu, Sinan, Maglic, Dejan, Fry, Elizabeth A., Kendig, Robert D., Inoue, Kazushi
Format: Artigo
Idioma:Inglês
Publicat: Libertas Academica 2011
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Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153120/
https://ncbi.nlm.nih.gov/pubmed/21836819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CMO.S7516
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