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Electrically monitoring DNA repair by photolyase

Cyclobutane pyrimidine dimers are the major DNA photoproducts produced upon exposure to UV radiation. If left unrepaired, these lesions can lead to replication errors, mutation, and cell death. Photolyase is a light-activated flavoenzyme that binds to pyrimidine dimers in DNA and repairs them in a r...

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Autors principals: DeRosa, Maria C., Sancar, Aziz, Barton, Jacqueline K.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182438/
https://ncbi.nlm.nih.gov/pubmed/16043698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503527102
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