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Bifurcating electron-transfer pathways in DNA photolyases determine the repair quantum yield
Photolyase is a blue-light–activated enzyme that repairs ultraviolet-induced DNA damage that occurs in the form of cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone (6–4) photoproducts. Previous studies on microbial photolyases have revealed an electron-tunneling pathway that is critica...
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| Veröffentlicht in: | Science |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7227132/ https://ncbi.nlm.nih.gov/pubmed/27738168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aah6071 |
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