Penetrance and Expressivity of MSH6 Germline Mutations in Seven Kindreds Not Ascertained by Family History

Hereditary nonpolyposis colorectal cancer (HNPCC) is caused by inherited mutations in DNA mismatch-repair genes, most commonly MLH1 or MSH2. The role MSH6 plays in inherited cancer susceptibility is less well defined. The aim of this study was to investigate the penetrance and expressivity of MSH6 m...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Buttin, Barbara M., Powell, Matthew A., Mutch, David G., Babb, Sheri A., Huettner, Phyllis C., Edmonston, Tina Bocker, Herzog, Thomas J., Rader, Janet S., Gibb, Randall K., Whelan, Alison J., Goodfellow, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society of Human Genetics 2004
Assuntos:
Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182090/
https://ncbi.nlm.nih.gov/pubmed/15098177
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares