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Thromboxane A(2)-induced contraction of rat caudal arterial smooth muscle involves activation of Ca(2+) entry and Ca(2+) sensitization: Rho-associated kinase-mediated phosphorylation of MYPT1 at Thr-855, but not Thr-697
The signal transduction pathway whereby the TxA(2) (thromboxane A(2)) mimetic U-46619 activates vascular smooth muscle contraction was investigated in de-endothelialized rat caudal artery. U-46619-evoked contraction was inhibited by the TP receptor (TxA(2) receptor) antagonist SQ-29548, the ROK (Rho...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Portland Press Ltd.
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1180727/ https://ncbi.nlm.nih.gov/pubmed/15823093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050237 |
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