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Selection of Genetic Markers for Association Analyses, Using Linkage Disequilibrium and Haplotypes

The genotyping of closely spaced single-nucleotide polymorphism (SNP) markers frequently yields highly correlated data, owing to extensive linkage disequilibrium (LD) between markers. The extent of LD varies widely across the genome and drives the number of frequent haplotypes observed in small regi...

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Detalhes bibliográficos
Main Authors: Meng, Zhaoling, Zaykin, Dmitri V., Xu, Chun-Fang, Wagner, Michael, Ehm, Margaret G.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180574/
https://ncbi.nlm.nih.gov/pubmed/12796855
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