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Selection of Genetic Markers for Association Analyses, Using Linkage Disequilibrium and Haplotypes

The genotyping of closely spaced single-nucleotide polymorphism (SNP) markers frequently yields highly correlated data, owing to extensive linkage disequilibrium (LD) between markers. The extent of LD varies widely across the genome and drives the number of frequent haplotypes observed in small regi...

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Bibliografiska uppgifter
Huvudupphovsmän: Meng, Zhaoling, Zaykin, Dmitri V., Xu, Chun-Fang, Wagner, Michael, Ehm, Margaret G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society of Human Genetics 2003
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180574/
https://ncbi.nlm.nih.gov/pubmed/12796855
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