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Selection of Genetic Markers for Association Analyses, Using Linkage Disequilibrium and Haplotypes

The genotyping of closely spaced single-nucleotide polymorphism (SNP) markers frequently yields highly correlated data, owing to extensive linkage disequilibrium (LD) between markers. The extent of LD varies widely across the genome and drives the number of frequent haplotypes observed in small regi...

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Auteurs principaux: Meng, Zhaoling, Zaykin, Dmitri V., Xu, Chun-Fang, Wagner, Michael, Ehm, Margaret G.
Format: Artigo
Langue:Inglês
Publié: The American Society of Human Genetics 2003
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180574/
https://ncbi.nlm.nih.gov/pubmed/12796855
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