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Correlation-Based Inference for Linkage Disequilibrium With Multiple Alleles

The correlation between alleles at a pair of genetic loci is a measure of linkage disequilibrium. The square of the sample correlation multiplied by sample size provides the usual test statistic for the hypothesis of no disequilibrium for loci with two alleles and this relation has proved useful for...

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Detalhes bibliográficos
Main Authors: Zaykin, Dmitri V., Pudovkin, Alexander, Weir, Bruce S.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2535703/
https://ncbi.nlm.nih.gov/pubmed/18757931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.089409
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