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Correlation-Based Inference for Linkage Disequilibrium With Multiple Alleles

The correlation between alleles at a pair of genetic loci is a measure of linkage disequilibrium. The square of the sample correlation multiplied by sample size provides the usual test statistic for the hypothesis of no disequilibrium for loci with two alleles and this relation has proved useful for...

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Autori principali: Zaykin, Dmitri V., Pudovkin, Alexander, Weir, Bruce S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2535703/
https://ncbi.nlm.nih.gov/pubmed/18757931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.089409
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