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Neutrophil elastase, an acid-independent serine protease, facilitates reovirus uncoating and infection in U937 promonocyte cells

BACKGROUND: Mammalian reoviruses naturally infect their hosts through the enteric and respiratory tracts. During enteric infections, proteolysis of the reovirus outer capsid protein σ3 is mediated by pancreatic serine proteases. In contrast, the proteases critical for reovirus replication in the lun...

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Detalhes bibliográficos
Main Authors: Golden, Joseph W, Schiff, Leslie A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180477/
https://ncbi.nlm.nih.gov/pubmed/15927073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-2-48
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