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Addition of Exogenous Protease Facilitates Reovirus Infection in Many Restrictive Cells

Virion uncoating is a critical step in the life cycle of mammalian orthoreoviruses. In cell culture, and probably in extraintestinal tissues in vivo, reovirus virions undergo partial proteolysis within endosomal or/or lysosomal compartments. This process converts the virion into a form referred to a...

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Hlavní autoři: Golden, Joseph W., Linke, Jessica, Schmechel, Stephen, Thoemke, Kara, Schiff, Leslie A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC136394/
https://ncbi.nlm.nih.gov/pubmed/12097555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.15.7430-7443.2002
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