Protective antibodies inhibit reovirus internalization and uncoating by intracellular proteases.

We identified in vitro correlates of in vivo protection mediated by nonneutralizing antibodies specific for reovirus capsid proteins. We defined mechanisms of antibody action by analyzing monoclonal antibody (MAb) effects at sequential steps in reovirus serotype 3 strain Dearing (T3D) infection of L...

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Bibliographic Details
Published in:J Virol
Main Authors: Virgin, H W, Mann, M A, Tyler, K L
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1994
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237093/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8084004/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.10.6719-6729.1994
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