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Addition of Exogenous Protease Facilitates Reovirus Infection in Many Restrictive Cells

Virion uncoating is a critical step in the life cycle of mammalian orthoreoviruses. In cell culture, and probably in extraintestinal tissues in vivo, reovirus virions undergo partial proteolysis within endosomal or/or lysosomal compartments. This process converts the virion into a form referred to a...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Golden, Joseph W., Linke, Jessica, Schmechel, Stephen, Thoemke, Kara, Schiff, Leslie A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136394/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12097555/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.15.7430-7443.2002
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