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Germline p53 Mutations in a Cohort with Childhood Sarcoma: Sex Differences in Cancer Risk

To characterize cancer risk in heterozygous p53 mutation carriers, we analyzed cancer incidence in 56 germline p53 mutation carriers and 3,201 noncarriers from 107 kindreds ascertained through patients with childhood soft-tissue sarcoma who were treated at the University of Texas M. D. Anderson Canc...

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Autori principali: Hwang, Shih-Jen, Lozano, Guillermina, Amos, Christopher I., Strong, Louise C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society of Human Genetics 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180359/
https://ncbi.nlm.nih.gov/pubmed/12610779
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