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Germline p53 Mutations in a Cohort with Childhood Sarcoma: Sex Differences in Cancer Risk

To characterize cancer risk in heterozygous p53 mutation carriers, we analyzed cancer incidence in 56 germline p53 mutation carriers and 3,201 noncarriers from 107 kindreds ascertained through patients with childhood soft-tissue sarcoma who were treated at the University of Texas M. D. Anderson Canc...

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Main Authors: Hwang, Shih-Jen, Lozano, Guillermina, Amos, Christopher I., Strong, Louise C.
Format: Artigo
Jezik:Inglês
Izdano: The American Society of Human Genetics 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180359/
https://ncbi.nlm.nih.gov/pubmed/12610779
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