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Toxoplasma gondii Cyclic GMP-Dependent Kinase: Chemotherapeutic Targeting of an Essential Parasite Protein Kinase

The trisubstituted pyrrole 4-[2-(4-fluorophenyl)-5-(1-methylpiperidine-4-yl)-1H-pyrrol-3-yl]pyridine (compound 1) has in vivo activity against the apicomplexan parasites Toxoplasma gondii and Eimeria tenella in animal models. The presumptive molecular target of this compound in E. tenella is cyclic...

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Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:Eukaryot Cell
Príomhchruthaitheoirí: Donald, Robert G. K., Allocco, John, Singh, Suresh B., Nare, Bakela, Salowe, Scott P., Wiltsie, Judyann, Liberator, Paul A.
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: American Society for Microbiology (ASM) 2002
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC118020/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12455981/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/EC.1.3.317-328.2002
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