Evolution of highly active enzymes by homology-independent recombination

The theta-class GST enzymes hGSTT1-1 (human GSTθ-1-1) and rGSTT2-2 (rat GSTθ-2-2) share 54.3% amino acid identity and exhibit different substrate specificities. Homology-independent techniques [incremental truncation for the creation of hybrid enzymes (ITCHY) and SCRATCHY] and low-homology technique...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Griswold, Karl E., Kawarasaki, Yasuaki, Ghoneim, Nada, Benkovic, Stephen J., Iverson, Brent L., Georgiou, George
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2005
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1177412/
https://ncbi.nlm.nih.gov/pubmed/16009931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504556102
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller